Description

5-o-Desosaminylerythronolide A Oxime is a key chemical intermediate in the synthesis of advanced macrolide antibiotics. This compound is of significant value in pharmaceutical research and development, particularly for creating novel antibacterial agents. It is primarily required by pharmaceutical manufacturers and R&D laboratories focused on antibiotic development and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of erythromycin-derived antibiotics and novel macrolide structures.
• Antibiotic Research & Development: Used in medicinal chemistry programs to develop new antibacterial compounds with improved efficacy or spectrum of activity.
• Process Chemistry & Scale-Up: Serves as a defined intermediate for optimizing and scaling production routes for complex active pharmaceutical ingredients (APIs).
• Biochemical Studies: Employed in research to study the structure-activity relationships (SAR) of macrolide antibiotics and their interaction with bacterial ribosomes.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control in API manufacturing.

Basic Information

Product Name	5-o-Desosaminylerythronolide A Oxime
CAS No.	53066-43-6
Molecular Formula	C37H66N2O12
Molecular Weight	730.93 g/mol
Synonyms	5-O-Desosaminylerythronolide A Oxime; Erythronolide A, 5-O-(3,4,6-trideoxy-3-dimethylamino-β-D-xylo-hexopyranosyl)-, oxime; (8S,9S,10R,11R,12R,13S,14R)-5-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-9,13-dihydroxy-2,4,6,8,10,12,14-heptamethyl-15-oxa-1-azabicyclo[10.2.1]pentadec-1-en-3-one oxime; Erythromycin A intermediate; Desosaminyl Erythronolide A Oxime
EINECS	Contact for details

Quality Control

Our 5-o-Desosaminylerythronolide A Oxime is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.