Description

Lithium Dimethylaminoborohydride 1M Solution in Tetrahydrofuran is a highly versatile and powerful reducing agent, offering superior selectivity and stability compared to traditional borohydrides. This compound is critical for synthetic chemists requiring controlled reduction of carbonyls, imines, and other functional groups under mild conditions. It is essential for advanced pharmaceutical synthesis, fine chemical manufacturing, and materials science research where precise and efficient hydride transfer is paramount.

Application

• Pharmaceutical Intermediate Synthesis: Selective reduction of ketones, aldehydes, and imines in the production of active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Employed as a chiral reducing agent in the synthesis of enantiomerically pure compounds.
• Polymer Chemistry: Used in the modification and cross-linking of polymers, and in the synthesis of boron-containing polymers.
• Fine Chemical Production: Key reagent for the reduction of sensitive substrates in multi-step synthetic sequences.
• Hydrogen Storage Materials Research: Investigated as a component or model compound in the development of novel chemical hydrogen storage systems.
• Academic & Industrial R&D: A staple reagent in research laboratories for methodology development and exploratory synthesis.

Basic Information

Product Name	Lithium Dimethylaminoborohydride 1M Solution in THF
CAS No.	53042-33-4
Molecular Formula	C₂H₉BLiN
Molecular Weight	76.89 g/mol
Synonyms	Lithium (Dimethylamino)borohydride; LiDMAB; Lithium Dimethylaminoborohydride; (Dimethylamino)borohydryl Lithium; Lithium (N,N-Dimethylamino)borohydride; Lithium (Dimethylamido)borohydride; Borate(1-), (dimethylamino)trihydro-, lithium, (T-4)-; Lithium (Dimethylamino)trihydroborate(1-)
EINECS	Contact for details

Quality Control

Our Lithium Dimethylaminoborohydride 1M Solution is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high performance. Each lot is analyzed to confirm concentration, purity, and suitability for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, solvent content, and impurity profile is provided with every shipment. Our quality system supports compliance with cGMP and ISO standards for research and commercial-scale use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dedicated, well-ventilated flammable solvents cabinet. The solution is moisture-sensitive and easily oxidized; ensure containers are sealed immediately after use to exclude air and moisture. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Concentration (in THF)	1.0 M ± 0.05 M
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.