Description

Methyl 2,3,4-Tri-o-Benzyl-α-D-Glucopyranoside CAS NO 53008-65-4 is a protected carbohydrate derivative, specifically a benzylated methyl glycoside, serving as a crucial chiral building block and synthetic intermediate. Its value lies in providing a stable, non-participating protecting group pattern for the hydroxyl functions of glucose, enabling selective deprotection and further functionalization in complex synthetic sequences. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for the synthesis of oligosaccharides, glycoconjugates, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex carbohydrate-based drugs, antiviral agents, and antibiotics.
• Glycochemistry Research: Fundamental building block for constructing oligosaccharides, glycopeptides, and glycomimetics in academic and industrial R&D.
• Glycosylation Reactions: Used as a glycosyl donor or acceptor in stereoselective glycosylation protocols to form specific glycosidic linkages.
• Protecting Group Strategy: The benzyl groups allow for orthogonal deprotection, enabling sequential synthesis of complex molecular architectures.
• Chemical Biology Probes: Intermediate in the preparation of labeled sugars or glycan arrays for studying carbohydrate-protein interactions.
• Process Development: Serves as a starting material or intermediate in scaling up the production of carbohydrate-active pharmaceuticals.

Basic Information

Item	Details
Product Name	Methyl 2,3,4-Tri-o-Benzyl-α-D-Glucopyranoside
CAS No.	53008-65-4
Molecular Formula	C28H32O6
Molecular Weight	464.55 g/mol
Synonyms	Methyl 2,3,4-Tri-O-benzyl-α-D-glucopyranoside; α-Methyl 2,3,4-Tri-O-benzyl-D-glucopyranoside; 1-O-Methyl-2,3,4-Tri-O-benzyl-α-D-glucopyranose; Methyl 2,3,4-Tri-O-benzyl-α-D-glucoside; 53008-65-4; α-D-Glucopyranoside, methyl 2,3,4-tris-O-(phenylmethyl)-; Methyl 2,3,4-Tri-O-benzylglucopyranoside
EINECS	Contact for details

Quality Control

Our Methyl 2,3,4-Tri-o-Benzyl-α-D-Glucopyranoside is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure high chemical and chiral purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.