Description

Caulophyllogenin is a triterpenoid saponin aglycone derived from the *Caulophyllum* genus of plants. This high-purity reference standard is critical for analytical research, quality control, and the development of phytopharmaceuticals. It serves as an essential building block for researchers and manufacturers in the pharmaceutical, nutraceutical, and botanical extract industries who require reliable, well-characterized compounds for their work.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the identification and quantification of Caulophyllogenin and related saponins in raw materials and finished products via HPLC, LC-MS, and TLC.
• Bioactivity Research: Employed in pharmacological studies to investigate potential anti-inflammatory, neuroprotective, or other therapeutic properties associated with triterpenoid compounds.
• Herbal Medicine Quality Control: A key marker compound for the standardization and authentication of botanical extracts from Blue Cohosh (*Caulophyllum thalictroides*) and other related medicinal plants.
• Nutraceutical Development: Serves as a standardized component in the formulation of high-quality, evidence-based dietary supplements.
• Chemical Synthesis Intermediate: Acts as a precursor or intermediate in the semi-synthesis of novel saponin derivatives for drug discovery programs.
• Academic & Institutional Research: Provides a pure compound for teaching and advanced research in natural product chemistry, phytochemistry, and pharmacognosy.

Basic Information

Product Name	Caulophyllogenin
CAS No.	52936-64-8
Molecular Formula	C30H48O4
Molecular Weight	472.71 g/mol
Synonyms	Caulophyllogenin; (3β,16β)-3,16-Dihydroxy-28-norolean-12-en-17-one; 28-Norolean-12-ene-3β,16β-diol-17-one; 3β,16β-Dihydroxy-28-norolean-12-en-17-one
EINECS	Contact for details

Quality Control

Our Caulophyllogenin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.