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2-Bromo-1-(2-Bromoethyl)-4-Chlorobenzene CAS NO 52927-98-7
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CAS No.:52927-98-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Bromo-1-(2-Bromoethyl)-4-Chlorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and chlorine substituents on a benzene ring with a bromoethyl side chain, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.
Application
- Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic motifs for bioactivity or as synthetic handles for further functionalization.
- Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the halogenated benzene core is integral to the molecule's mode of action.
- Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
- Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, or polymers where halogen atoms can influence electronic properties and intermolecular interactions.
- Cross-Coupling Reactions: The bromine atoms provide excellent sites for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) enabling rapid diversification of the molecular scaffold.
- Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems, leveraging the halogens as tags or for further bioconjugation.
Basic Information
| Product Name | 2-Bromo-1-(2-Bromoethyl)-4-Chlorobenzene |
| CAS No. | 52927-98-7 |
| Molecular Formula | C8H7Br2Cl |
| Molecular Weight | 298.40 g/mol |
| Synonyms | 1-(2-Bromoethyl)-2-bromo-4-chlorobenzene; 2-Bromo-4-chloro-1-(2-bromoethyl)benzene; 4-Chloro-1-(2-bromoethyl)-2-bromobenzene; 1,2-Dibromo-4-chlorophenylethane; (2-Bromoethyl)-2-bromo-4-chlorobenzene; Benzene, 2-bromo-1-(2-bromoethyl)-4-chloro-; 52927-98-7 |
| EINECS | Contact for details |
Quality Control
Our 2-Bromo-1-(2-Bromoethyl)-4-Chlorobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder or solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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