Description

3-Hydroxy-2-Phenylpropionitrile is a versatile chiral building block and intermediate in organic synthesis. Its value lies in the presence of both a nitrile and a hydroxyl group on a phenylpropane backbone, enabling a range of chemical transformations. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of β-blockers, adrenergic agents, and other bioactive molecules.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Research: Serves as a building block for developing novel herbicides and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: A potential monomer or intermediate for creating advanced polymers with specific optical properties.
• Academic & R&D Laboratories: Employed in methodological studies for asymmetric synthesis and catalysis.

Basic Information

Product Name	3-Hydroxy-2-Phenylpropionitrile
CAS No.	52923-48-5
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	2-Phenyl-3-hydroxypropionitrile; 3-Hydroxy-2-phenylpropanenitrile; (RS)-3-Hydroxy-2-phenylpropionitrile; (±)-3-Hydroxy-2-phenylpropionitrile; DL-3-Hydroxy-2-phenylpropionitrile; 3-Hydroxy-2-phenylpropiononitrile; β-Hydroxy-β-phenylpropionitrile; Phenylhydroxypropionitrile
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-Phenylpropionitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.