Description

4-Methyl-2-Isobutyloxy-1,3,2-Dioxaborolane is a specialized organoboron reagent belonging to the class of cyclic boronic esters. This compound is valued for its role as a key intermediate and protecting group in advanced organic synthesis, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity boron-containing building blocks for developing active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A crucial boron reagent for forming carbon-carbon bonds between aryl/vinyl halides and boronic acids/esters.
• Pharmaceutical Intermediate Synthesis: Used in constructing complex molecular scaffolds for active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Serves as a building block for synthesizing novel herbicides, fungicides, and insecticides.
• Materials Science & Polymer Chemistry: Employed in the synthesis of organic electronic materials, OLEDs, and functional polymers.
• Boronic Acid & Ester Protection: Acts as a protecting group for boronic acids, enhancing their stability and handling properties during multi-step syntheses.
• Catalyst & Ligand Development: Utilized in the preparation of novel boron-based catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	4-Methyl-2-Isobutyloxy-1,3,2-Dioxaborolane
CAS No.	52910-21-1
Molecular Formula	C8H17BO3
Molecular Weight	172.03 g/mol
Synonyms	2-Isobutoxy-4-methyl-1,3,2-dioxaborolane; 4-Methyl-2-(2-methylpropoxy)-1,3,2-dioxaborolane; Isobutyl 4-methyl-1,3,2-dioxaborolan-2-yl ether; Pinanediol isobutyl boronate (related cyclic ester); Cyclic isobutyl boronate ester; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-Isobutyloxy-1,3,2-Dioxaborolane is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with the standards required for cGMP and ISO 9001 environments, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition and maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.