Description

2-Propenoic Acid, 2-Methyl-, Tetrahydro-2H-Pyran-2-Yl Ester is a specialized methacrylate derivative featuring a tetrahydro-2H-pyran-2-yl protecting group, offering unique reactivity and stability profiles for advanced synthesis. This compound is valued for its role as a versatile monomer and intermediate, enabling the creation of polymers with tailored properties and serving as a key building block in organic transformations. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients, functional coatings, and specialty polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, leveraging the protecting group for selective deprotection.
• Advanced Polymer Synthesis: Serves as a functional monomer for creating specialty acrylic and methacrylic polymers with controlled architecture for coatings, adhesives, and resins.
• Agrochemical Development: Employed as a key intermediate in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Cross-linking Agent: Utilized in formulations for UV-curable inks, coatings, and photoresists due to its reactive methacrylate functionality.
• Organic Synthesis Building Block: Acts as a protected acrylic acid equivalent in multi-step synthetic routes for fine chemicals and complex molecules.
• Material Science Research: Investigated for developing novel hydrogels, biocompatible materials, and stimuli-responsive polymers.

Basic Information

Product Name	2-Propenoic Acid, 2-Methyl-, Tetrahydro-2H-Pyran-2-Yl Ester
CAS No.	52858-59-0
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	2-Methyl-2-propenoic acid tetrahydro-2H-pyran-2-yl ester; Methacrylic acid tetrahydro-2H-pyran-2-yl ester; THP-Methacrylate; Tetrahydro-2H-pyran-2-yl methacrylate; 2-(Methacryloyloxy)tetrahydropyran; THPMA; 2-Methylacrylic acid oxan-2-yl ester; 2-Propenoic acid, 2-methyl-, 2-tetrahydropyranyl ester
EINECS	Contact for details

Quality Control

Our production of 2-Propenoic Acid, 2-Methyl-, Tetrahydro-2H-Pyran-2-Yl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assessment and identity confirmation. A Certificate of Analysis (COA) detailing specific results for assay, impurities, and physical properties is provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ISO, and other relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat sources and open flames. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Refractive Index (20°C)	1.460 - 1.470
Density (20°C)	1.02 - 1.06 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.