Description

3'-Bromo-2'-Methylacetophenone is a versatile brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its structure, featuring both a reactive carbonyl group and a bromine substituent on the aromatic ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with substituted acetophenone or aryl ketone backbones.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where its halogenated structure is incorporated into the final molecule.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions due to the presence of the bromine atom.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and the exploration of new synthetic pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	3'-Bromo-2'-Methylacetophenone
CAS No.	52779-76-7
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	1-(3-Bromo-2-methylphenyl)ethanone; 3'-Bromo-2'-methylacetophenone; 2-Methyl-3-bromoacetophenone; 3-Bromo-2-methylacetophenone; 1-Acetyl-3-bromo-2-methylbenzene; 2'-Methyl-3'-bromoacetophenone; α-Bromo-o-methylacetophenone (isomer specific); Ethanone, 1-(3-bromo-2-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 3'-Bromo-2'-Methylacetophenone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.