Description

2-Butanone Diethyl Acetal is a specialized acetal derivative of 2-butanone (methyl ethyl ketone), serving as a versatile protecting group reagent and synthetic intermediate in advanced organic synthesis. Its primary value lies in its ability to mask carbonyl functionalities under acidic conditions, enabling selective transformations in complex multi-step syntheses. This high-purity chemical is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular construction is critical.

Application

• As a carbonyl protecting group in multi-step organic synthesis, particularly for ketones.
• Key synthetic intermediate in the production of pharmaceuticals and active pharmaceutical ingredients (APIs).
• Precursor in the manufacture of specialty fragrances, flavors, and aroma chemicals.
• Used in agrochemical research for the synthesis of novel herbicides and pesticides.
• Employed in acetalization reactions to create monomers for specialty polymers.
• Solvent and reagent in laboratory-scale research and process development.

Basic Information

Product Name	2-Butanone Diethyl Acetal
CAS No.	52752-16-6
Molecular Formula	C8H18O2
Molecular Weight	146.23 g/mol
Synonyms	Methyl Ethyl Ketone Diethyl Acetal; Butan-2-one Diethyl Acetal; 1,1-Diethoxybutane; Ethyl Methyl Ketone Diethyl Acetal; Diethyl Butan-2-ylidene Orthoether; 2-Butanone, Diethyl Acetal; 1,1-Diethoxy-2-butanone (common misnomer)
EINECS	Contact for details

Quality Control

Our 2-Butanone Diethyl Acetal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.395 - 1.405
Density (20°C)	0.825 - 0.835 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.