Description

2-Bromo-5'-Chloro-2'-Hydroxyacetophenone is a specialized halogenated acetophenone derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its unique molecular structure, featuring both bromo and chloro substituents on the aromatic ring, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing molecules with potential therapeutic activity.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, where its halogenated structure contributes to biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to create complex biaryl and heterocyclic systems.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: A versatile reagent for academic and industrial labs exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	2-Bromo-5'-Chloro-2'-Hydroxyacetophenone
CAS No.	52727-99-8
Molecular Formula	C8H6BrClO2
Molecular Weight	249.49 g/mol
Synonyms	1-(2-Bromo-5-chloro-2-hydroxyphenyl)ethanone; 2'-Hydroxy-2-bromo-5'-chloroacetophenone; 2-Bromo-5-chloro-2'-hydroxyacetophenone; 5'-Chloro-2-bromo-2'-hydroxyacetophenone; α-Bromo-5-chloro-2-hydroxyacetophenone; NSC 403796
EINECS	Contact for details

Quality Control

Our 2-Bromo-5'-Chloro-2'-Hydroxyacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.