Description

Bis(4-Nitrophenyl) Phosphorochloridothioate is a specialized organophosphorus compound primarily used as a key synthetic intermediate. Its value lies in its reactive phosphorochloridothioate group, which enables the efficient construction of complex phosphorus-containing molecules. This high-purity chemical is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries developing novel active ingredients and advanced materials.

Application

• Agrochemical Intermediate: A critical building block in the synthesis of novel insecticides, herbicides, and fungicides, particularly those with thiophosphoryl or phosphorothioate backbones.
• Pharmaceutical Research: Used in medicinal chemistry for the development of potential drug candidates, enzyme inhibitors, and prodrugs containing phosphorus moieties.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized phosphine ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Polymer Modification: Employed to introduce phosphorus-based functional groups into polymers to impart specific properties like flame retardancy or metal chelation.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and mechanism in biological systems.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymeric materials and coatings.

Basic Information

Product Name	Bis(4-Nitrophenyl) Phosphorochloridothioate
CAS No.	52678-80-5
Molecular Formula	C12H8ClN2O5PS
Molecular Weight	358.69 g/mol
Synonyms	Phosphorochloridothioic Acid, O,O-Bis(4-nitrophenyl) Ester; O,O-Bis(p-Nitrophenyl) Phosphorochloridothioate; Phosphorochloridothioic Acid Bis(4-nitrophenyl) Ester; Bis(p-Nitrophenyl) Chlorothiophosphate; 4-Nitrophenyl Chlorothiophosphate; DNPPCT; BNPCT
EINECS	Contact for details

Quality Control

Every batch of Bis(4-Nitrophenyl) Phosphorochloridothioate is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to support research and development as well as scale-up activities, ensuring the material meets your precise specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.