Description

(8R,13S)-13-(Hydroxymethyl)-17-Norkaur-15-Ene-1α,12β-Diol is a high-purity, semi-synthetic diterpenoid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex natural product analogs, terpenoid-based drug candidates, and specialized fine chemicals. Its defined stereochemistry and functional groups make it a valuable scaffold for medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in oncology and metabolic disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the synthesis of terpenoid-inspired compound libraries.
• Natural Product Synthesis: Serves as a sophisticated intermediate in the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of high-value fine chemicals.
• Biochemical Research: Potential use as a probe or standard in studying enzymatic pathways related to terpenoid biosynthesis.
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(8R,13S)-13-(Hydroxymethyl)-17-Norkaur-15-Ene-1α,12β-Diol
CAS No.	52591-20-5
Molecular Formula	C₁₉H₃₀O₃
Molecular Weight	306.44 g/mol
Synonyms	13-(Hydroxymethyl)-17-norkaur-15-en-1α,12β-diol; 17-Norkaur-15-ene-1α,12β-diol, 13-(hydroxymethyl)-, (8R,13S)-; Kaurane diterpenoid derivative; Diterpene alcohol intermediate; (1α,12β,8R,13S)-13-(Hydroxymethyl)kaur-15-en-17-oic acid derivative; NSC 339586; Ent-13-(Hydroxymethyl)kaur-15-en-1α,12β-diol
EINECS	Contact for details

Quality Control

Our (8R,13S)-13-(Hydroxymethyl)-17-Norkaur-15-Ene-1α,12β-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment supports compliance with research and development standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under anhydrous conditions if necessary to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.