Description

3-(Chloromethyl)-p-Anisaldehyde is a versatile aromatic aldehyde building block featuring both a reactive aldehyde group and a chloromethyl substituent. This bifunctional nature makes it a critical intermediate for synthesizing more complex molecules in advanced chemical manufacturing. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting specific receptors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and advanced materials requiring specific aromatic architectures.
• Polymer Modification: The chloromethyl group allows for grafting onto polymer backbones to create functionalized materials with tailored properties.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to form complex biaryl structures.

Basic Information

Product Name	3-(Chloromethyl)-p-Anisaldehyde
CAS No.	52577-09-0
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	4-Methoxy-3-(chloromethyl)benzaldehyde; 3-(Chloromethyl)-4-methoxybenzaldehyde; p-Anisaldehyde, 3-(chloromethyl)-; 4-Methoxy-3-chloromethylbenzaldehyde; 3-Chloromethyl-4-methoxybenzaldehyde; 3-(Chloromethyl)-4-anisaldehyde; 52577-09-0; 4-Methoxy-3-(chloromethyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)-p-Anisaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.