Description

Pyrimidine, 2-[(Trimethylsilyl)Oxy]- (9Ci) is a specialized organosilicon-protected pyrimidine derivative, serving as a key synthetic intermediate. Its value lies in providing a protected hydroxyl functionality on the pyrimidine ring, enabling complex multi-step synthesis in controlled environments. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require high-purity, moisture-sensitive building blocks for advanced R&D and production.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate pyrimidine motifs.
• Organic Synthesis & Research: Serves as a versatile protected intermediate for constructing complex heterocyclic compounds in academic and industrial laboratories.
• Material Science Precursor: Potential use in the development of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	Pyrimidine, 2-[(Trimethylsilyl)Oxy]- (9Ci)
CAS No.	52523-22-5
Molecular Formula	C7H12N2OSi
Molecular Weight	168.27 g/mol
Synonyms	2-(Trimethylsilyloxy)pyrimidine; 2-Trimethylsilyloxypyrimidine; O-(Trimethylsilyl)pyrimidin-2-ol; Pyrimidin-2-ol, trimethylsilyl ether; 2-(Trimethylsiloxy)pyrimidine; TMS-protected 2-hydroxypyrimidine; 2-OTMS-pyrimidine
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 2-[(Trimethylsilyl)Oxy]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.