Description

(20S)-20,24-Epoxy-3β,30-Dihydroxy-22,24-Dimethyl-26,27-Dinor-5α-Dammar-22-En-16-One is a high-purity, semi-synthetic dammarane-type triterpenoid derivative. This compound is valued for its role as a critical pharmaceutical intermediate and a versatile scaffold in medicinal chemistry research. It is primarily sought by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel triterpenoid-based drug candidates targeting metabolic and inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Natural Product Derivative Synthesis: A starting material for creating analogs of bioactive natural products like ginsenosides for enhanced efficacy.
• Biochemical Research: Investigated for its potential interactions with enzymes and receptors in preclinical studies.
• Fine Chemical Production: Employed in multi-step synthetic routes to produce specialized, high-value chemical entities.

Basic Information

Product Name	(20S)-20,24-Epoxy-3β,30-Dihydroxy-22,24-Dimethyl-26,27-Dinor-5α-Dammar-22-En-16-One
CAS No.	52470-19-6
Molecular Formula	C₃₀H₄₈O₄
Molecular Weight	472.70 g/mol
Synonyms	20(S),24-Epoxy-3β,30-dihydroxy-22,24-dimethyl-26,27-dinor-5α-dammar-22-en-16-one; 20(S)-Protopanaxadiol Epoxide; 20(S)-PPD Epoxide; 20(S)-AP Epoxide; 20(S)-Aglycone Epoxide; Dammar-22-en-16-one, 20,24-epoxy-3,30-dihydroxy-22,24-dimethyl-26,27-dinor-, (3β,5α,20S)-; Ginsenoside Aglycone Epoxide Derivative
EINECS	Contact for details

Quality Control

Our (20S)-20,24-Epoxy-3β,30-Dihydroxy-22,24-Dimethyl-26,27-Dinor-5α-Dammar-22-En-16-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.