Description

5,6,7-Trihydroxy-18-Methyloxacyclooctadecan-2-One is a complex, high-purity macrolide derivative of significant interest in advanced chemical synthesis. This compound matters for its potential as a key chiral intermediate or building block in the development of specialized pharmaceuticals and fine chemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and high-value synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel macrolide antibiotics and other complex active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in advanced organic synthesis for constructing complex molecular architectures, leveraging its multiple functional groups for selective reactions.
• Biochemical Research: Acts as a reference standard or a substrate in enzymatic studies and metabolic pathway research due to its specific stereochemistry.
• Agrochemical Development: Potential intermediate in the research and development of new, high-efficacy crop protection agents with novel modes of action.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying ring-closing reactions, hydroxyl group manipulations, and asymmetric synthesis.

Basic Information

Product Name	5,6,7-Trihydroxy-18-Methyloxacyclooctadecan-2-One
CAS No.	52461-08-2
Molecular Formula	C₁₈H₃₄O₅
Molecular Weight	330.46 g/mol
Synonyms	18-Methyl-5,6,7-trihydroxyoxacyclooctadecan-2-one; (2R,5S,6S,7S,18S)-18-Methyl-5,6,7-trihydroxyoxacyclooctadecan-2-one (stereospecific); A related macrolide lactone intermediate; 5,6,7-Trihydroxy-18-methyloxacyclooctadec-2-one; Potential derivative of Oleandomycin or similar macrolide.
EINECS	Contact for details

Quality Control

Our 5,6,7-Trihydroxy-18-Methyloxacyclooctadecan-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity (typically by HPLC), and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be opaque or stored in dark conditions. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee (by Chiral HPLC)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.