Description

2-(Bromomethyl)-1-Chloro-4-Nitrobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring reactive bromomethyl, chloro, and nitro substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex aromatic backbones.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides where the nitro and halogen groups are essential for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex azo dyes and other colored compounds.
• Ligand and Catalyst Development: Useful for creating novel chelating ligands in coordination chemistry and catalysis.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical research.

Basic Information

Product Name	2-(Bromomethyl)-1-Chloro-4-Nitrobenzene
CAS No.	52427-01-7
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	1-Chloro-2-(bromomethyl)-4-nitrobenzene; 2-Bromomethyl-1-chloro-4-nitrobenzene; 4-Nitro-2-(bromomethyl)chlorobenzene; (2-Bromomethyl-4-nitrophenyl)chloride; 1-Chloro-4-nitro-2-(bromomethyl)benzene; Benzene, 1-chloro-2-(bromomethyl)-4-nitro-; α-Bromo-2-chloro-5-nitrobenzyl bromide (historical)
EINECS	Contact for details

Quality Control

Our production of 2-(Bromomethyl)-1-Chloro-4-Nitrobenzene adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Quality is verified through modern analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials. Due to its light-sensitive nature and potential as a strong oxidizer, maintain storage temperatures between 15-25°C (59-77°F) and ensure segregation from reducing agents and other combustible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.