Description

1-Bromo-2-(1,1,2,3,3,3-Hexafluoropropoxy)Benzene is a specialized fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of a reactive bromine substituent and a highly fluorinated alkoxy side chain, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, leveraging the fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced pesticides and herbicides where the fluorinated moiety enhances lipophilicity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Polymer & Specialty Chemical Modification: Employed to introduce fluorinated aromatic ether groups into polymers, imparting properties like chemical resistance and low surface energy.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination strategies and structure-activity relationships.

Basic Information

Product Name	1-Bromo-2-(1,1,2,3,3,3-Hexafluoropropoxy)Benzene
CAS No.	52328-77-5
Molecular Formula	C9H5BrF6O
Molecular Weight	323.03 g/mol
Synonyms	2-Bromo-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; o-Bromohexafluoropropyl phenyl ether; 1-Bromo-2-(hexafluoroisopropoxy)benzene; Benzene, 1-bromo-2-(1,1,2,3,3,3-hexafluoropropoxy)-; 2-(1,1,2,3,3,3-Hexafluoropropoxy)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-(1,1,2,3,3,3-Hexafluoropropoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.