Description

(1R)-3α-Acetyl-2,2-Dimethylcyclobutane-1α-Acetic Acid CAS NO 52305-34-7 is a high-purity, chiral cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex, biologically active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, fragrances, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring stereochemical control.
• Agrochemical Synthesis: Used in the creation of novel, high-performance pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing unique musk-like or woody fragrance compounds due to its constrained cyclobutane ring structure.
• Material Science Research: Investigated as a monomer or building block for novel polymers and advanced organic materials with specific structural properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development of new asymmetric catalytic processes.
• Academic & Industrial R&D: Utilized in chemical research for method development and the exploration of new reaction pathways involving strained ring systems.

Basic Information

Product Name	(1R)-3α-Acetyl-2,2-Dimethylcyclobutane-1α-Acetic Acid
CAS No.	52305-34-7
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	(1R)-3-Acetyl-2,2-dimethylcyclobutane-1-acetic acid; (1R)-3α-Acetyl-2,2-dimethylcyclobutane-1α-acetic acid; (1R,3S)-3-Acetyl-2,2-dimethylcyclobutane-1-acetic acid; (1R)-3-Acetyl-2,2-dimethyl-1-cyclobutanecarboxylic acid; (1R)-2,2-Dimethyl-3-acetylcyclobutane-1-acetic acid; (1R)-Homoaconic acid derivative; Chiral cyclobutane acetic acid derivative
EINECS	Contact for details

Quality Control

Our (1R)-3α-Acetyl-2,2-Dimethylcyclobutane-1α-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.