Description

Caprolactone, Polyethylene Glycol Polymer is a high-performance, biodegradable block copolymer synthesized from ε-caprolactone and polyethylene glycol (PEG). This versatile material is engineered to combine the hydrophobic, crystalline properties of polycaprolactone (PCL) with the hydrophilic, flexible characteristics of PEG, creating a unique amphiphilic structure. It is essential for formulators and manufacturers seeking advanced, biocompatible materials for controlled-release systems, tissue engineering, and specialty coatings. Key industries that rely on this polymer include pharmaceuticals, biomedical devices, and advanced material science.

Application

• Drug Delivery Systems: As a key excipient for creating biodegradable microspheres, nanoparticles, and implants for sustained and targeted release of active pharmaceutical ingredients (APIs).
• Biomedical & Tissue Engineering: Used in the fabrication of scaffolds for cell growth, wound dressings, and absorbable surgical sutures due to its biocompatibility and tunable degradation rate.
• Specialty Coatings & Adhesives: Serves as a modifier to enhance the flexibility, adhesion, and biodegradability of coatings for agricultural films, packaging, and eco-friendly adhesives.
• Personal Care & Cosmetics: Employed in advanced skincare formulations as a film-forming agent, encapsulant for active ingredients, and to provide controlled moisturization.
• 3D Printing (Additive Manufacturing): A functional material for bioprinting and fabricating custom medical devices with precise mechanical and degradation properties.
• Hydrogel Formulation: Acts as a macromer or cross-linker to create hydrogels with specific swelling behaviors and mechanical strength for biomedical applications.

Basic Information

Product Name	Caprolactone, Polyethylene Glycol Polymer
CAS No.	52284-06-7
Molecular Formula	(C6H10O2)m-(C2H4O)n
Molecular Weight	Variable (Depends on m/n ratio)
Synonyms	PCL-PEG Copolymer; Poly(ε-caprolactone)-block-poly(ethylene glycol); PEG-PCL Diblock Copolymer; Poly(ethylene glycol)-block-poly(caprolactone); Polycaprolactone-Polyethylene Glycol Block Copolymer; PCL-b-PEG; Amphiphilic PCL-PEG; Poly(oxyethylene)-block-poly(oxycaproyl)
EINECS	Contact for details

Quality Control

Our Caprolactone, Polyethylene Glycol Polymer is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure consistent molecular weight distribution, block ratio, purity, and performance. Certificates of Analysis (COA) detailing specifications for identity, assay, residual monomers, and endotoxin levels (where applicable) are provided. We support compliance with cGMP, ISO 13485, and relevant pharmacopeial guidelines for biomedical-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen) to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white waxy solid or flakes
Identification (IR)	Conforms to structure
Assay (PCL/PEG Ratio)	As per customer requirement (e.g., 50:50, 70:30)
Molecular Weight (Mn)	1,000 - 20,000 Da (Customizable)
Polydispersity Index (PDI)	≤ 1.5
Residual ε-Caprolactone	≤ 0.5%
Residual Solvent	Meets ICH guidelines
Water Content	≤ 1.0%
Melting Point	40 - 60°C (Varies with composition)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.