Description

2,2,2-Trifluoro-n-(2,2,2-Trifluoro-1-Trifluoromethyl-Ethylidene)-Acetamide is a highly fluorinated acetamide derivative, a specialized building block prized for its unique chemical reactivity and stability imparted by the trifluoromethyl groups. This compound is critical for introducing fluorine atoms into complex molecular architectures, a key strategy in modern material and pharmaceutical science. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging fluorine's ability to improve lipophilicity and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and electronic materials requiring specific thermal, chemical, or surface properties.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated components in display and lighting technologies, where fluorine atoms help tune electronic properties and improve device performance.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in academic and industrial research for constructing complex, fluorinated organic molecules and exploring new catalytic pathways.
• Surface Modification Agent: Used to create low-surface-energy, hydrophobic, and oleophobic coatings for textiles, optics, and electronic components.

Basic Information

Item	Details
Product Name	2,2,2-Trifluoro-n-(2,2,2-Trifluoro-1-Trifluoromethyl-Ethylidene)-Acetamide
CAS No.	52225-57-7
Molecular Formula	C6HF9NO
Molecular Weight	277.06 g/mol
Synonyms	N-(Perfluoro-tert-butyl)trifluoroacetamide; 2,2,2-Trifluoro-N-(1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-ylidene)acetamide; 1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)-2-propanimine, N-(trifluoroacetyl)-; Perfluoro-tert-butyl trifluoroacetimide; Hexafluoroacetone Trifluoroacetimide; (Perfluoro-tert-butyl)trifluoroacetimidoyl fluoride (related); TFAA-HFIP Imine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(2,2,2-Trifluoro-1-Trifluoromethyl-Ethylidene)-Acetamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.