Description

2-Bromo-3',5'-Dipivaloxyacetophenone is a specialized organic intermediate featuring a brominated acetophenone core protected with pivaloyl groups. This compound matters as a versatile and reactive building block, enabling precise synthetic modifications in complex organic synthesis. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and fine chemical industries for constructing advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Organic Synthesis Reagent: Used in cross-coupling reactions, nucleophilic substitutions, and as a precursor for further functionalization.
• Chemical Research: Serves as a critical reagent in academic and industrial R&D for exploring new synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemical intermediates, and advanced materials.
• Ligand and Catalyst Development: Potential use in the preparation of novel ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Bromo-3',5'-Dipivaloxyacetophenone
CAS No.	52223-86-6
Molecular Formula	C18H23BrO4
Molecular Weight	383.28 g/mol
Synonyms	1-(2-Bromo-3,5-bis(2,2-dimethylpropanoyloxy)phenyl)ethan-1-one; 2'-Bromo-3',5'-di-O-pivaloylacetophenone; 2-Bromo-3,5-bis(pivaloyloxy)acetophenone; Acetophenone, 2-bromo-3',5'-bis(2,2-dimethyl-1-oxopropoxy)-; 2-Bromo-3,5-di-tert-butoxycarbonyloxyacetophenone (common name variant); BK-3',5'-DPA (abbreviation); 52223-86-6 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2-Bromo-3',5'-Dipivaloxyacetophenone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.