Description

2,3-Dihydroxy-(2Alpha,3Alpha)-Urs-12-En-28-Oic Acid Methyl Ester is a high-purity pentacyclic triterpenoid derivative, valued for its role as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is essential for researchers and manufacturers developing novel therapeutic agents, particularly in the fields of oncology, metabolic disorders, and anti-inflammatory drugs. Its defined stereochemistry and functional groups make it a sought-after building block for producing more complex bioactive molecules and reference standards.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the semi-synthesis of novel ursane-type triterpenoid drugs targeting inflammation and cancer.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for the identification and quantification of ursolic acid derivatives in herbal extracts and finished products.
• Biochemical Research: Employed in academic and industrial R&D to study structure-activity relationships (SAR), enzyme inhibition, and metabolic pathways.
• Nutraceutical Development: Serves as a precursor for enhancing the bioavailability and efficacy of triterpenoid-based dietary supplements.
• Cosmeceutical Actives: Investigated for use in advanced skincare formulations for its potential anti-aging and protective properties.

Basic Information

Item	Details
Product Name	2,3-Dihydroxy-(2Alpha,3Alpha)-Urs-12-En-28-Oic Acid Methyl Ester
CAS No.	52213-28-2
Molecular Formula	C₃₁H₅₀O₄
Molecular Weight	490.73 g/mol
Synonyms	Methyl 2α,3α-Dihydroxyurs-12-en-28-oate; 2α,3α-Dihydroxyurs-12-en-28-oic Acid Methyl Ester; Urs-12-ene-2α,3α,28-triol Methyl Ether; Methyl 2,3-Dihydroxyurs-12-en-28-oate; 2,3-Dihydroxyursolic Acid Methyl Ester; Methyl Dihydroxyursolate; (2α,3α)-2,3-Dihydroxyurs-12-en-28-oic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydroxy-(2Alpha,3Alpha)-Urs-12-En-28-Oic Acid Methyl Ester is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles verified by HPLC, NMR, and MS. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and research, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.