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Rac-(S*)-2-(Acetylamino)-3-Methylbutanoic Acid Methyl Ester CAS NO 52152-47-3


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CAS No.:52152-47-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rac-(S*)-2-(Acetylamino)-3-Methylbutanoic Acid Methyl Ester is a high-purity chiral building block and protected amino acid derivative. This compound is essential for the synthesis of complex peptides and active pharmaceutical ingredients (APIs), offering a versatile intermediate for introducing specific stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and process development.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based therapeutics and small molecule drugs.
  • Peptide Synthesis: Used as a protected amino acid ester in solid-phase and solution-phase peptide synthesis.
  • Chemical Research: Serves as a valuable building block in medicinal chemistry for structure-activity relationship (SAR) studies.
  • Process Chemistry: Employed in the scale-up and optimization of synthetic routes for target molecules in pilot plants and commercial manufacturing.
  • Bioconjugation: Potential use in the modification of biomolecules for creating targeted drug delivery systems.
  • Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in GMP environments.

Basic Information

Product Name Rac-(S*)-2-(Acetylamino)-3-Methylbutanoic Acid Methyl Ester
CAS No. 52152-47-3
Molecular Formula C8H15NO3
Molecular Weight 173.21 g/mol
Synonyms N-Acetyl-DL-valine methyl ester; Methyl N-acetyl-DL-valinate; DL-N-Acetylvaline methyl ester; Methyl 2-acetamido-3-methylbutanoate; 2-Acetamido-3-methylbutyric acid methyl ester; Ac-DL-Val-OMe; (RS)-2-Acetamido-3-methylbutanoic acid methyl ester
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Quality Control

Our Rac-(S*)-2-(Acetylamino)-3-Methylbutanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Purity (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Optical Purity (Chiral HPLC) Racemic mixture

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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