Description

1-(2-Iodo-5-Methylphenyl)Ethanone is a specialized aromatic ketone building block featuring both iodo and methyl substituents on the phenyl ring. This compound matters as a versatile intermediate for constructing more complex molecules, particularly in pharmaceutical and advanced material synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic structures.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the iodo group facilitates further derivatization.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and photoactive materials due to its electron-accepting carbonyl group and halogen atom.
• Cross-Coupling Reactions: Essential substrate in palladium-catalyzed reactions such as Suzuki, Sonogashira, and Heck couplings for carbon-carbon bond formation.
• Organic Synthesis Laboratory: A valuable reagent for academic and industrial research in constructing complex organic molecules and exploring new synthetic methodologies.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	1-(2-Iodo-5-Methylphenyl)Ethanone
CAS No.	52107-82-1
Molecular Formula	C9H9IO
Molecular Weight	260.07 g/mol
Synonyms	2'-Iodo-5'-methylacetophenone; 1-(2-Iodo-5-methylphenyl)ethan-1-one; 2-Acetyl-4-iodotoluene; 5-Methyl-2-iodoacetophenone; 2-Iodo-5-methylacetophenone; Ethanone, 1-(2-iodo-5-methylphenyl)-; o-Iodo-p-methylacetophenone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity organic intermediates. We provide comprehensive analytical data including HPLC purity, identity confirmation by FT-IR and NMR spectroscopy, and quantification of key impurities. Certificates of Analysis (COA) are available upon request for every batch, detailing all relevant specifications to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent photodegradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.