Description

4-Fluoro-2-Methyl-1-Indanone is a high-purity fluorinated indanone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced material science industries seeking to introduce specific fluorinated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals with tailored electronic and optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, cyclizations, and as a substrate for further functionalization in medicinal chemistry research.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular conformation and reactivity.

Basic Information

Product Name	4-Fluoro-2-Methyl-1-Indanone
CAS No.	52045-42-8
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	4-Fluoro-2-methylindan-1-one; 2-Methyl-4-fluoro-1-indanone; 1-Indanone, 4-fluoro-2-methyl-; 4-Fluoro-2-methyl-2,3-dihydro-1H-inden-1-one; 52045-42-8; FC-IMK
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methyl-1-Indanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.