Description

1-Butanone, 1-(5-Chloro-2-Hydroxyphenyl)- is a specialized chlorinated aromatic ketone derivative with significant utility as a key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking a high-purity building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those with chlorinated phenolic structures.
• Agrochemical Synthesis: Serves as a key precursor in the manufacture of advanced herbicides, fungicides, and pesticides, leveraging its reactive ketone and phenolic groups.
• Fine Chemical Production: Used in the preparation of complex dyes, pigments, and specialty chemicals requiring a chlorinated hydroxybenzophenone core.
• Research & Development: Employed in academic and industrial R&D laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with specific optical or thermal properties.

Basic Information

Product Name	1-Butanone, 1-(5-Chloro-2-Hydroxyphenyl)-
CAS No.	51978-33-7
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	5'-Chloro-2'-hydroxybutyrophenone; 1-(5-Chloro-2-hydroxyphenyl)-1-butanone; 5-Chloro-2-hydroxybutyrophenone; 4-Chloro-2-butyrylphenol; Butanone, 1-(5-chloro-2-hydroxyphenyl)-; 2-Butanoyl-4-chlorophenol; 4-Chloro-2-(1-oxobutyl)phenol; 1-Butanone,1-(5-chloro-2-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 1-Butanone, 1-(5-Chloro-2-Hydroxyphenyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC and GC analysis, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.