Description

Trifluoromethylphosphonic Acid Dichloride is a high-value organophosphorus building block characterized by its reactive dichloride and trifluoromethyl groups. This compound is essential for the synthesis of advanced ligands, catalysts, and biologically active molecules where the introduction of a phosphonic acid derivative or a fluorine-containing moiety is required. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Used to create advanced herbicides, pesticides, and plant growth regulators with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a critical building block for phosphonate-based ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Flame Retardant Additives: Intermediate for producing phosphorus- and fluorine-containing flame retardants for polymers and electronics.
• Surface Modification Agents: Used to create self-assembled monolayers (SAMs) or to functionalize surfaces with specific chemical properties.
• Chemical Research & Development: A versatile reagent in organic synthesis for introducing the -PO(Cl)2 and -CF3 functional groups into target molecules.

Basic Information

Product Name	Trifluoromethylphosphonic Acid Dichloride
CAS No.	51965-64-1
Molecular Formula	C2HCl2F3O2P
Molecular Weight	198.90 g/mol
Synonyms	Phosphonic Dichloride, (Trifluoromethyl)-; (Trifluoromethyl)phosphonic Dichloride; Trifluoromethylphosphonyl Dichloride; CF3PO(O)Cl2; 2,2,2-Trifluoroethylphosphonic Dichloride; α,α,α-Trifluoromethylphosphonic Dichloride
EINECS	Contact for details

Quality Control

Our Trifluoromethylphosphonic Acid Dichloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay by GC or NMR, identity confirmation (IR), and impurity profiling, to ensure it meets the high-purity standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and sources of moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.