Description

3-Trifluoroacetyl-D-Camphor is a high-value, chiral fluorinated derivative of camphor, distinguished by its trifluoroacetyl functional group. This compound is a critical chiral building block and ligand in asymmetric synthesis, offering significant utility in the preparation of enantiomerically pure pharmaceuticals and specialty chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors where precise stereochemical control is paramount.

Application

• As a key chiral ligand or auxiliary in asymmetric catalytic reactions, including aldol condensations and alkylations.
• As a versatile building block for the synthesis of complex, fluorinated active pharmaceutical ingredients (APIs).
• In the research and development of novel agrochemicals requiring specific stereochemistry for enhanced activity.
• For the preparation of specialty chemicals and advanced materials where fluorination imparts unique properties.
• As a reference standard or intermediate in analytical chemistry and process development for chiral compounds.
• In academic and industrial research focused on organofluorine chemistry and stereoselective synthesis methodologies.

Basic Information

Product Name	3-Trifluoroacetyl-D-Camphor
CAS No.	51800-98-7
Molecular Formula	C₁₂H₁₅F₃O₂
Molecular Weight	248.24 g/mol
Synonyms	(1R,4S)-1,7,7-Trimethyl-3-(trifluoroacetyl)bicyclo[2.2.1]heptan-2-one; D-3-Trifluoroacetylcamphor; (1R)-(-)-3-Trifluoroacetylcamphor; (-)-3-Trifluoroacetylcamphor; 3-(Trifluoroacetyl)-(1R)-camphor; (1R,2S,4R)-(-)-3-Trifluoroacetylcamphor; TFAC; 3-TFA Camphor
EINECS	Contact for details

Quality Control

Our 3-Trifluoroacetyl-D-Camphor is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by methods such as HPLC, GC, and NMR, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.