Description

4-Fluoro-2-Methoxyacetophenone is a versatile fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-donating methoxy and electron-withdrawing fluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated liquid crystal molecules and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and the exploration of new fluorination reactions and heterocyclic chemistry.
• Flavor & Fragrance Intermediate: Acts as a precursor for synthesizing specific aromatic compounds used in high-value fragrance and flavor formulations.

Basic Information

Product Name	4-Fluoro-2-Methoxyacetophenone
CAS No.	51788-80-8
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	1-(4-Fluoro-2-methoxyphenyl)ethanone; 4'-Fluoro-2'-methoxyacetophenone; 2-Methoxy-4-fluoroacetophenone; 4-Fluoro-2-methoxyacetophenone; 4-Fluoro-2-methoxy-1-acetylbenzene; 1-Acetyl-4-fluoro-2-methoxybenzene; 4-Fluoro-o-methoxyacetophenone; Ethanone, 1-(4-fluoro-2-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxyacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.