Description

Dimethyl 5-Bromoisophthalate is a high-purity brominated aromatic diester, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of specialty polymers and active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce bromine functionality for further cross-coupling or substitution reactions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a brominated isophthalate core for further functionalization.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for brominated aromatic monomers used in the production of high-performance liquid crystals and organic light-emitting diode (OLED) materials.
• Polymer & Resin Modification: Used to introduce bromine atoms into polymer backbones (e.g., polyesters, polyamides) to impart flame retardancy or to create reactive sites for grafting.
• Agrochemical Synthesis: Intermediate in the manufacture of certain herbicides and fungicides where the bromine substituent is crucial for biological activity.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Ligand & Catalyst Preparation: Used in the synthesis of specialized ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing novel aromatic compounds.

Basic Information

Product Name	Dimethyl 5-Bromoisophthalate
CAS No.	51760-21-5
Molecular Formula	C10H9BrO4
Molecular Weight	273.08 g/mol
Synonyms	5-Bromoisophthalic Acid Dimethyl Ester; Dimethyl 5-Bromo-1,3-benzenedicarboxylate; 1,3-Benzenedicarboxylic acid, 5-bromo-, dimethyl ester; 5-Bromo-isophthalic acid dimethyl ester; 5-Bromobenzene-1,3-dicarboxylic acid dimethyl ester; 5-Bromo-1,3-benzenedicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our Dimethyl 5-Bromoisophthalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.