Description

(3R,5R,6S,7S,9R,11E,13S,14R)-3,5,7,9,13-Pentamethyl-6,13-Dihydroxy-14-Ethyl-1-Oxacyclotetradeca-11-Ene-2,4,10-Trione is a complex macrolide derivative with a defined stereochemistry, making it a valuable chiral building block and intermediate for advanced chemical synthesis. Its intricate structure is critical for research and development in creating novel compounds with specific biological activities. This high-purity intermediate is essential for pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on stereoselective synthesis and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel macrolide antibiotics and other complex therapeutic agents.
• Agrochemical Research: Used in the development of new, targeted pesticides and fungicides where specific stereochemistry influences bioactivity.
• Chemical Synthesis: Acts as a sophisticated building block for organic chemists exploring new catalytic methodologies and natural product analogs.
• Academic & Institutional Research: Employed in universities and research institutes for studying macrolide chemistry, total synthesis projects, and structure-activity relationships (SAR).
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for complex molecules in pilot plants.

Basic Information

Item	Detail
Product Name	(3R,5R,6S,7S,9R,11E,13S,14R)-3,5,7,9,13-Pentamethyl-6,13-Dihydroxy-14-Ethyl-1-Oxacyclotetradeca-11-Ene-2,4,10-Trione
CAS No.	51724-55-1
Molecular Formula	C21H32O7
Molecular Weight	396.48 g/mol
Synonyms	2,4,10-Trioxo-3,5,7,9,13-pentamethyl-6,13-dihydroxy-14-ethyl-1-oxacyclotetradec-11-ene; 14-Ethyl-3,5,7,9,13-pentamethyl-6,13-dihydroxy-1-oxacyclotetradeca-11-ene-2,4,10-trione; Macrolide derivative 51724-55-1; (3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-3,5,7,9,13-pentamethyl-6,13-dihydroxy-1-oxacyclotetradec-11-ene-2,4,10-trione
EINECS	Contact for details

Quality Control

Our (3R,5R,6S,7S,9R,11E,13S,14R)-3,5,7,9,13-Pentamethyl-6,13-Dihydroxy-14-Ethyl-1-Oxacyclotetradeca-11-Ene-2,4,10-Trione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.