Description

Methyl 3-Oxoisobutyrate is a versatile organic ester and a key chemical intermediate valued for its reactive β-ketoester functionality. This compound is essential for the synthesis of complex molecules, offering a crucial building block for constructing heterocycles and fine-tuning molecular properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing pyrimidine and pyridine rings.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactivity to form complex heterocyclic structures.
• Fine Chemical Production: Serves as a fundamental building block for synthesizing flavors, fragrances, and other specialty organic compounds.
• Research & Development: Employed in academic and industrial R&D labs for method development and the creation of novel chemical entities.
• Polymer Chemistry: Can be utilized as a monomer or modifier in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	Methyl 3-Oxoisobutyrate
CAS No.	51673-64-4
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	Methyl 3-oxobutyrate; Methyl acetoacetate (Note: This is a common synonym, though strictly refers to the linear isomer); 3-Oxobutyric acid methyl ester; Methyl 3-oxobutanoate; Acetoacetic acid methyl ester; Methyl β-ketobutyrate; MAA (abbreviation); 51673-64-4
EINECS	257-307-5

Quality Control

Our Methyl 3-Oxoisobutyrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed after use to minimize moisture uptake and evaporation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.