Description

2-Bromo-4,5-dimethoxyphenylacetonitrile is a versatile and high-value brominated aromatic nitrile building block. Its unique structure, featuring both bromine and nitrile functional groups on a dimethoxybenzene scaffold, makes it a critical intermediate for synthesizing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It serves as a key precursor in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used as a precursor in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport molecules or nonlinear optical (NLO) chromophores.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical companies offering bespoke synthesis services to the life sciences sector.

Basic Information

Item	Details
Product Name	2-Bromo-4,5-Dimethoxyphenylacetonitrile
CAS No.	51655-39-1
Molecular Formula	C10H10BrNO2
Molecular Weight	256.10 g/mol
Synonyms	2-Bromo-4,5-dimethoxybenzyl cyanide; (2-Bromo-4,5-dimethoxyphenyl)acetonitrile; α-Bromo-3,4-dimethoxyphenylacetonitrile; 4,5-Dimethoxy-2-bromophenylacetonitrile; 2-Bromo-4,5-dimethoxybenzeneacetonitrile; 51655-39-1; (2-Bromo-4,5-dimethoxyphenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,5-dimethoxyphenylacetonitrile is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment, ensuring full traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.