Description

4'-Piperazinoacetophenone is a high-purity organic intermediate featuring a piperazine-substituted acetophenone core structure. This compound is of significant value in pharmaceutical research and development, serving as a versatile building block for the synthesis of more complex active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chemical Synthesis Building Block: Used in organic synthesis to introduce the 4-piperazinylacetophenone moiety into larger molecular frameworks.
• Research & Development: Essential for medicinal chemistry programs in academic and industrial laboratories for structure-activity relationship (SAR) studies.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Ligand Synthesis: Can be utilized for the preparation of ligands used in catalysis or biochemical assays.

Basic Information

Product Name	4'-Piperazinoacetophenone
CAS No.	51639-48-6
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	1-[4-(1-Piperazinyl)phenyl]ethanone; 4-Acetylphenylpiperazine; 4'-Acetylpiperazine; 1-(4-Piperazin-1-ylphenyl)ethanone; p-Acetylphenylpiperazine; 4-Piperazin-1-ylacetophenone; Ethanone, 1-[4-(1-piperazinyl)phenyl]-; 4-Piperazinoacetophenone
EINECS	Contact for details

Quality Control

Our 4'-Piperazinoacetophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.