Description

Cyclopropanecarboxamide, 1-Cyano-2,2-Difluoro- (9Ci) is a high-purity, specialized fluorinated cyclopropane derivative identified by CAS No. 51550-07-3. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in creating novel pesticides and herbicides where the difluorocyclopropane moiety can enhance biological activity and metabolic stability.
• Material Science Precursor: Employed in the development of specialty polymers and advanced materials with unique fluorinated properties.
• Organic Synthesis Building Block: Facilitates [2+1] cycloaddition and other ring-forming reactions to construct complex, strained molecular architectures.
• Ligand and Catalyst Development: Serves as a scaffold for designing novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Research: Essential for academic and industrial research exploring the effects of gem-difluoro substitution on molecular conformation and reactivity.

Basic Information

Product Name	Cyclopropanecarboxamide, 1-Cyano-2,2-Difluoro- (9Ci)
CAS No.	51550-07-3
Molecular Formula	C5H4F2N2O
Molecular Weight	146.10 g/mol
Synonyms	1-Cyano-2,2-difluorocyclopropanecarboxamide; 2,2-Difluoro-1-cyanocyclopropanecarboxamide; 2,2-Difluorocyclopropane-1-carboxamide, 1-cyano-; 1-Cyano-2,2-difluorocyclopropane-1-carboxamide; Difluorocyclopropanecarbonitrile carboxamide; (1-Cyano-2,2-difluorocyclopropyl)formamide
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxamide, 1-Cyano-2,2-Difluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.