Description

2-Bromo-1-(3,4,5-Trimethoxy-Phenyl)-Ethanone is a versatile brominated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in its reactive bromomethyl ketone moiety, which serves as a key electrophile for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those with complex heterocyclic or substituted aromatic cores.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive site for molecular diversification.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Material Science Precursor: Potential use in the synthesis of monomers or functionalized molecules for advanced polymeric materials.

Basic Information

Item	Details
Product Name	2-Bromo-1-(3,4,5-Trimethoxy-Phenyl)-Ethanone
CAS No.	51490-01-8
Molecular Formula	C11H13BrO4
Molecular Weight	289.12 g/mol
Synonyms	2-Bromo-1-(3,4,5-trimethoxyphenyl)ethanone; 3',4',5'-Trimethoxy-2-bromoacetophenone; 2-Bromo-3,4,5-trimethoxyacetophenone; 1-(3,4,5-Trimethoxyphenyl)-2-bromoethanone; NSC 403169; Ethanone, 2-bromo-1-(3,4,5-trimethoxyphenyl)-; α-Bromo-3,4,5-trimethoxyacetophenone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(3,4,5-Trimethoxy-Phenyl)-Ethanone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.