Description

cis-Ormeloxifene is a selective estrogen receptor modulator (SERM) with a distinct stereochemical configuration. This compound is of significant interest in pharmaceutical research and development due to its specific biological activity profile. It is primarily utilized by researchers and manufacturers in the life sciences sector for the development of novel therapeutic agents and for advanced biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of advanced therapeutic compounds.
• Biomedical Research: Used as a reference standard and active agent in studies targeting estrogen receptor pathways.
• Drug Discovery & Development: Employed in preclinical research for evaluating efficacy and mechanism of action in relevant disease models.
• Academic Research: Utilized in university and institutional labs for fundamental studies in endocrinology and cancer biology.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories.

Basic Information

Product Name	cis-Ormeloxifene
CAS No.	51423-19-9
Molecular Formula	C29H35NO2
Molecular Weight	429.60 g/mol
Synonyms	Centchroman; Ormeloxifene; cis-Centchroman; (3R,4S)-7-Methoxy-3-methyl-2-phenyl-4-(4-(2-pyrrolidin-1-ylethoxy)phenyl)chroman; 67/20; NNC 46-0020; Centron; Saheli; Sevista
EINECS	Contact for details

Quality Control

Our cis-Ormeloxifene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% cis-isomer
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.