Description

1-[5-(4-Chlorophenyl)-2-Thienyl]-1-Ethanone is a high-purity organic building block featuring a chlorophenyl-substituted thiophene ketone structure. This compound is valued for its role as a critical synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its bioactive heterocyclic core.
• Material Science Research: Serves as a monomer or building block for developing organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Potential precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-[5-(4-Chlorophenyl)-2-Thienyl]-1-Ethanone
CAS No.	51335-90-1
Molecular Formula	C12H9ClOS
Molecular Weight	236.71 g/mol
Synonyms	1-(5-(4-Chlorophenyl)thiophen-2-yl)ethanone; 4'-Chloro-2-acetylthiophene; 2-Acetyl-5-(4-chlorophenyl)thiophene; 5-(p-Chlorophenyl)-2-acetylthiophene; 1-[5-(4-Chlorophenyl)-2-thienyl]ethanone; 2-Acetyl-5-(4'-chlorophenyl)thiophene; Ethanone, 1-[5-(4-chlorophenyl)-2-thienyl]-
EINECS	Contact for details

Quality Control

Our 1-[5-(4-Chlorophenyl)-2-Thienyl]-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.