Description

(+)-cis-1(R),2(S)-1,2-Dihydroxy-1,2-Dihydronaphthalene is a high-purity chiral diol derivative of naphthalene, serving as a critical synthetic intermediate and building block. Its defined stereochemistry makes it an invaluable precursor for the synthesis of complex, optically active molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists working on chiral ligands, catalysts, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where stereochemistry influences biological activity.
• Catalyst & Ligand Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating novel polymers and advanced organic materials with specific optical properties.
• Fine Chemical Synthesis: Employed in academic and industrial R&D for constructing complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	(+)-cis-1(R),2(S)-1,2-Dihydroxy-1,2-Dihydronaphthalene
CAS No.	51268-88-3
Molecular Formula	C₁₀H₁₀O₂
Molecular Weight	162.19 g/mol
Synonyms	(1R,2S)-1,2-Dihydroxy-1,2-dihydronaphthalene; (+)-cis-1,2-Dihydroxy-1,2-dihydronaphthalene; (1R,2S)-1,2-Dihydroxy-1,2,3,4-tetrahydronaphthalene; cis-(1R,2S)-1,2-Dihydroxy-1,2-dihydronaphthalene; Naphthalene cis-dihydrodiol; (1R,2S)-Naphthalene-1,2-diol; (1R,2S)-1,2,3,4-Tetrahydro-1,2-naphthalenediol
EINECS	Contact for details

Quality Control

Our (+)-cis-1(R),2(S)-1,2-Dihydroxy-1,2-Dihydronaphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.