Description

Cyclopropanecarboxylic Acid, 2-Cyano-1-Ethenyl-, Methyl Ester, trans- (9Ci) is a specialized, high-purity chemical intermediate characterized by its unique cyclopropane and cyanoacrylate functional groups. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering a versatile scaffold for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce cyclopropane rings and reactive handles into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent in the development of specialty polymers and coatings, leveraging the reactivity of the cyanoacrylate group.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, such as cycloaddition reactions and the construction of complex heterocycles.
• Liquid Crystal & OLED Materials: Acts as a precursor in the synthesis of advanced electronic materials requiring specific stereochemistry and polarizable groups.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Cyano-1-Ethenyl-, Methyl Ester, trans- (9Ci)
CAS No.	51171-67-6
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	trans-2-Cyano-1-ethenylcyclopropanecarboxylic acid methyl ester; Methyl trans-2-cyano-1-vinylcyclopropanecarboxylate; (1R,2S)-rel-2-Cyano-1-ethenylcyclopropanecarboxylic Acid Methyl Ester; trans-Methyl 2-cyano-1-vinylcyclopropanecarboxylate; 2-Cyano-1-ethenylcyclopropanecarboxylic Acid Methyl Ester, (1R,2S)-rel-; Cyclopropanecarboxylic acid, 2-cyano-1-ethenyl-, methyl ester, (1R,2S)-rel-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Cyano-1-Ethenyl-, Methyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee reliable performance in your sensitive synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.