Description

Z-Trp-Val-Oh is a protected tripeptide derivative, specifically the Z-protected form of the Tryptophan-Valine dipeptide. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for the development of therapeutic peptides and complex organic molecules.

Application

• Pharmaceutical Intermediates: Key raw material in the synthesis of novel therapeutic peptides for drug discovery and development.
• Peptide Synthesis: Essential building block (amino acid derivative) for solid-phase and solution-phase peptide synthesis.
• Biochemical Research: Used in academic and industrial R&D for studying peptide structure, function, and bioactivity.
• Protecting Group Chemistry: Serves as a model compound in methodologies involving the Z (benzyloxycarbonyl) protecting group.
• Custom Peptide Production: Employed by CROs and CDMOs for the contract manufacturing of specific peptide sequences.

Basic Information

Product Name	Z-Trp-Val-Oh
CAS No.	51126-85-3
Molecular Formula	C26H29N3O5
Molecular Weight	463.53 g/mol
Synonyms	N-Carbobenzyloxy-L-tryptophyl-L-valine; Z-L-Tryptophyl-L-valine; Z-Trp-Val; Z-Tryptophan-Valine; Nα-Z-L-Tryptophyl-L-valine; Benzyloxycarbonyl-L-tryptophyl-L-valine; CBZ-L-Tryptophyl-L-valine; N-CBZ-L-Tryptophyl-L-valine
EINECS	Contact for details

Quality Control

Our Z-Trp-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing identity, purity, and related substances are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.