Description

(4α)-2β-Hydroxy-15-Oxo-19-Norkauran-18-Oic Acid is a high-purity, semi-synthetic diterpenoid derivative of the kaurane class. This compound serves as a critical advanced intermediate in pharmaceutical research and synthesis, valued for its complex, functionalized ring structure. It is primarily utilized by research institutions and fine chemical manufacturers engaged in the development of novel therapeutic agents and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop analogs with enhanced biological activity.
• Natural Product Synthesis: Serves as a sophisticated precursor in the total or semi-synthesis of complex diterpenoid natural products.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and compound identification.
• Biochemical Research: Investigated for its potential interactions with specific enzymes or biological pathways due to its unique stereochemistry.

Basic Information

Product Name	(4α)-2β-Hydroxy-15-Oxo-19-Norkauran-18-Oic Acid
CAS No.	51107-83-6
Molecular Formula	C₁₉H₂₈O₄
Molecular Weight	320.43 g/mol
Synonyms	19-Norkauran-18-oic acid, 2β-hydroxy-15-oxo-, (4α)-; 2β-Hydroxy-15-oxo-19-norkauran-18-oic acid; 15-Oxo-2β-hydroxy-19-norkauran-18-oic acid; ent-2β-Hydroxy-15-oxo-19-norkauran-18-oic acid; KA-003; A derivative of ent-Kaur-16-en-19-oic acid
EINECS	Contact for details

Quality Control

Our (4α)-2β-Hydroxy-15-Oxo-19-Norkauran-18-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.