Description

6-Bromo-4-Chloro-3-Formylcoumarin is a versatile and highly functionalized coumarin derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of reactive bromo, chloro, and formyl groups on the coumarin scaffold, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting cancer, inflammation, and infectious diseases.
• Agrochemical Research: Used in creating advanced pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Fluorescent Probe & Dye Synthesis: Serves as a precursor for developing coumarin-based fluorescent dyes and molecular probes used in bioimaging and sensors.
• Organic Synthesis & Material Science: A versatile substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and the preparation of complex organic materials.
• Chemical Biology Tool: Utilized in the design and synthesis of enzyme inhibitors and other bioactive molecules for mechanistic studies.

Basic Information

Product Name	6-Bromo-4-Chloro-3-Formylcoumarin
CAS No.	51069-90-0
Molecular Formula	C10H4BrClO3
Molecular Weight	287.50 g/mol
Synonyms	4-Chloro-6-bromo-3-formylcoumarin; 3-Formyl-6-bromo-4-chlorocoumarin; 6-Bromo-4-chloro-3-formyl-2H-chromen-2-one; 6-Bromo-4-chloro-2-oxo-2H-chromene-3-carbaldehyde; 2H-1-Benzopyran-2-one, 6-bromo-4-chloro-3-formyl-; 6-Bromo-4-chloro-3-formyl-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-3-Formylcoumarin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.