Description

2-Bromo-3-Methylacetophenone is a versatile brominated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists in fine chemical, pharmaceutical, and material science industries seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing substituted acetophenone or bromoaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the bromo-methylacetophenone structure imparts specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in various name reactions, including Friedel-Crafts acylation follow-ups, nucleophilic substitutions, and cross-coupling reactions to introduce complex side chains.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and pigments due to its aromatic ketone structure.

Basic Information

Product Name	2-Bromo-3-Methylacetophenone
CAS No.	51012-64-7
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	1-(2-Bromo-3-methylphenyl)ethanone; 2'-Bromo-3'-methylacetophenone; 3-Methyl-2-bromoacetophenone; o-Bromo-m-methylacetophenone; 2-Bromo-3-methyl-1-phenylethanone; 1-Acetyl-2-bromo-3-methylbenzene; Ethanone, 1-(2-bromo-3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methylacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.