Description

2-Methyl-1-[3,3,3-Trifluoro-1-Oxo-2-(Trifluoromethyl)Propyl]Azetidine is a high-value, fluorinated azetidine derivative characterized by its unique trifluoromethyl and keto functional groups. This compound matters as a sophisticated building block and key intermediate in advanced synthetic chemistry, enabling the introduction of fluorine atoms to modulate the properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in developing advanced pesticides and herbicides where the fluorine atoms contribute to improved environmental stability and efficacy.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of specialty polymers with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in organometallic chemistry to construct novel ligands for catalysis, leveraging the azetidine ring's constrained geometry.
• Fluorine Chemistry Research: A valuable substrate for studying new fluorination methodologies and the behavior of polyfluorinated systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	2-Methyl-1-[3,3,3-Trifluoro-1-Oxo-2-(Trifluoromethyl)Propyl]Azetidine
CAS No.	50837-79-1
Molecular Formula	C9H9F6NO
Molecular Weight	261.16 g/mol
Synonyms	1-(3,3,3-Trifluoro-2-(trifluoromethyl)propanoyl)-2-methylazetidine; 2-Methyl-1-(3,3,3-trifluoro-2-(trifluoromethyl)propanoyl)azetidine; 2-Methylazetidine, 1-[3,3,3-trifluoro-1-oxo-2-(trifluoromethyl)propyl]-; N-[3,3,3-Trifluoro-2-(trifluoromethyl)propionyl]-2-methylazetidine; Fluorinated Azetidine Keto Derivative
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-1-[3,3,3-Trifluoro-1-Oxo-2-(Trifluoromethyl)Propyl]Azetidine adheres to a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.