Description

(1R,4R)-Methyl 4-(Aminomethyl)Cyclohexanecarboxylate is a high-purity, stereochemically defined chiral building block of significant importance in advanced organic synthesis. Its rigid cyclohexane backbone, combined with both ester and primary amine functional groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is particularly valuable for pharmaceutical research and development, where it serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and antiviral medications.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Peptidomimetics & Bioactive Molecule Design: The aminomethyl and ester groups facilitate its incorporation into peptide backbones and other bioactive scaffolds to modulate pharmacokinetic properties.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Can be used to introduce functional amine groups into polymer chains for specialty materials.
• Research & Development: An essential tool in academic and industrial R&D for exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	(1R,4R)-Methyl 4-(Aminomethyl)Cyclohexanecarboxylate
CAS No.	50738-63-1
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Methyl (1R,4R)-4-(aminomethyl)cyclohexanecarboxylate; (1R,4R)-4-(Aminomethyl)cyclohexanecarboxylic acid methyl ester; trans-Methyl 4-(aminomethyl)cyclohexanecarboxylate; (1R,4R)-Rel-(aminomethyl)cyclohexanecarboxylic acid methyl ester; (1R,4R)-Methyl 4-aminomethyl-1-cyclohexanecarboxylate; (1R,4R)-4-Carbomethoxycyclohexylmethylamine; trans-4-(Aminomethyl)cyclohexanecarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (1R,4R)-Methyl 4-(Aminomethyl)Cyclohexanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.