Description

2-Chloro-1-(2,4,6-Trimethyl-Phenyl)-Ethanone is a specialized organic building block featuring a halogenated ketone structure adjacent to a sterically hindered mesitylene ring. This compound matters as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique reactivity is leveraged. It is needed by research and development chemists, process development scientists, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted acetophenone core.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the chloro and trimethylphenyl groups impart specific biological activity.
• Organic Synthesis Building Block: Acts as a versatile electrophile in Friedel-Crafts acylation reactions and nucleophilic substitution reactions for constructing complex aromatic ketones and heterocycles.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies and the development of new synthetic pathways.

Basic Information

Item	Detail
Product Name	2-Chloro-1-(2,4,6-Trimethyl-Phenyl)-Ethanone
CAS No.	50690-12-5
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	2-Chloro-1-(2,4,6-trimethylphenyl)ethanone; 2-Chloro-1-mesitylethanone; 2-Chloro-2',4',6'-trimethylacetophenone; 2-Chloro-1-(2,4,6-trimethylphenyl)ethan-1-one; α-Chloromesityl methyl ketone; 50690-12-5; Ethanone, 2-chloro-1-(2,4,6-trimethylphenyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(2,4,6-Trimethyl-Phenyl)-Ethanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics, supporting compliance with cGMP and other relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.