Description

Tetrahydropyran-4-Carbaldehyde is a versatile heterocyclic aldehyde building block of significant importance in synthetic organic chemistry. Its unique structure, featuring a protected aldehyde group within a tetrahydropyran ring, makes it a valuable intermediate for constructing complex molecular architectures. This compound is particularly sought after by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing piperidine or morpholine analogs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the tetrahydropyran moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers, dendrimers, and liquid crystals.
• Chemical Biology Probes: Useful for creating molecular probes and tags due to its reactive aldehyde functionality.
• Fragrance and Flavor Chemistry: Acts as a building block for certain aroma chemicals and flavor compounds.

Basic Information

Product Name	Tetrahydropyran-4-Carbaldehyde
CAS No.	50675-18-8
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	4-Formyltetrahydropyran; Tetrahydropyran-4-carboxaldehyde; 4-Oxanylformaldehyde; 4-Formyloxane; 4-Tetrahydropyranecarboxaldehyde; Oxan-4-carbaldehyde; THP-4-Carbaldehyde
EINECS	256-673-7

Quality Control

Our Tetrahydropyran-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.455
Density (g/mL, 20°C)	1.05 - 1.10

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.